Agenda

Conference Agenda

Full speaker bios are also available

Day 1 (Tuesday, March 8th)

Opening Plenary: 10:00 a.m. – 10:45 a.m.
• “Reaching the Goal of Personalized Medicine: What hills are left to climb?”
o Leroy Hood, Institute for Systems Biology

Session I: Creating Knowledge, Applying Knowledge: 10:45 a.m. – 12:10 p.m.

• “From data comes knowledge - but there are hurdles”
o Scott Jenkins, Dell Healthcare & Life Sciences (Session Chair)
• “Data resources and data generation hurdles”
o Jack Collins, National Cancer Institute
• “Algorithmic hurdles to predictive marker discovery”
o Nanguneri Nirmala, Novartis
• “Tiered computational strategies”
o Raymond Ng, University of British Columbia/ The PROOF Centre of Excellence
• “Knowledge building environments”
o Kashef Qaadri, IO Informatics, Inc.

Session II: Tools for Personalized Medicine: 12:55 p.m. – 2:05 p.m.

• “Personalization - are we there yet?”
o Bruce McManus, The PROOF Centre of Excellence (Session Chair)
• “ETL, integration, quality assurance, and provenance hurdles”
o Ted Slater, Merck & Co., Inc.
• “How do GWAS, NextGen sequencing, microRNAs, and ‘-OMICs’ relate?”
o Sergio Baranzini, University of California, San Francisco,
• “The need for critical appraisal of surrogates”
o Garrett FitzGerald, Institute for the Translational Medicine and Therapeutics
• “Can tools for personalized medicine meet the promise? How soon?”
o Tim Triche, Childrens Hospital Los Angeles

Session III: Healthcare Systems: 2:05 p.m. – 3:15 p.m.

• “Can complex health systems adapt for higher quality in the face of fiscal constraint?”
o Heather Manson, The Ontario Agency for Health Protection and Promotion (Session Chair)
• “Business models for personalized medicine
o Christopher-Paul Milne, Tufts Center for the Study of Drug Development
• “Affordability of marker-based diagnostics
o Carlo Marra, Collaboration for Outcomes Research and Evaluation (CORE)
• “Diversity of revenue and cost-centered models
o Scott Ramsey, Fred Hutchinson Cancer Research Center

Expert Forum & Discussion I: 3:35 p.m. – 5:00 p.m.
“What we heard, what we didn’t, what we need to learn”

Day 2 (Wednesday, March 9th)

Session IV: Patient Characterization and Cohorts: 8:30 a.m. – 9:40 a.m.

• “Essential considerations in patient and cohort characterization”
o Rob Beanlands, University of Ottawa Heart Institute (Session Chair)
• “Essential ingredients for phenotyping”
o Peter Watson, UBC/ BC Cancer Agency's Vancouver Island Centre
• “Workable privacy and ethical framework for expeditions in translational research”
o Bartha Knoppers, Université de Montréal
• “Engagement of patient cohorts for better medicines, faster”
o Ramesh Ramanathan, TGen Clinical Research Services (TCRS)

Session V: Regulatory Matters: 9:40 a.m. – 10:50 a.m.

• “Regulatory challenges and opportunities in the era of molecular solutions for health care”
• “Standards for validation - clarity or diversity”
o Elaine Tseng, King & Spalding
• Path to bring new tools, tests, and therapeutics to bear on human health
o John Ferguson, Novartis Vaccines & Diagnostics
• Intellectual property - is there an easier way to social and economic value?
o Andrew Serafini, Fenwick

Session VI: Data Access and Sharing: 11:05 a.m. – 12:15 p.m.

• “Challenges and Value to sharing data in the Life Sciences”
o Sean Mooney, Buck Institute for Age Research (Session Chair)
• “Managing large semantic knowledge bases”
o Victor Zak, Oracle
• “Data sharing success stories”
o Scott Marshall, Leiden University Medical Center
• “Technologies, methods and challenges to effective public data sharing and aggregation”
o Mark Wilkinson, University of British Columbia

Session VII: EHR/ EMR: 1:00 p.m. – 2:25 p.m.

• “The future of personalized healthcare is now - leveraging new forms of patient information”
o Kareem Saad, Dell Healthcare & Life Sciences (Session Chair)
• “Accessing the golden therapeutic window via standards based personalized medicine”
o Pete Tassiopoulos, Biosign Technologies Inc.
• “Crowd-sourcing better medical decisions”
o Chris Yoo, MedTrust Online
• “Information residing in molecular diagnostic and genomic laboratory services”
o Azita Sharif, Daedalus Software

Session VIII: Delivering Personalized Care: 2:25 p.m. – 3:35 p.m.

• “Building consortia for enhanced predictive, diagnostic and therapeutic care”
o David Wholley, The Biomarkers Consortium at the Foundation for the NIH (Session Chair)
• “What can biotech bring to personalization?”
o Daniel Bednarik, Cardiome Pharma
• “Strategies and barriers to deliver personalization to the point of care”
o Brad Popovich, Genome British Columbia
• “ASK for confident decisions: Harnessing the power of semantics"
o Erich Gombocz, IO Informatics, Inc.

Expert Forum & Discussion II: 3:50 p.m. – 5:20 p.m.
“What we heard, what we didn’t, what we need to learn”